| ncRNA name | hsa-miR-17 |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples, normal retina tissues; human RB cell line Y79 |
| Methods | qRT-PCR, transfection, MTT assay, transwell assay, Western blot, Caspase-3 assay |
| Expression pattern | up-regulated |
| Functional description | This study has showed varied expression of the miR17-92 cluster in primary RB tumors. EpCAM influences miR 17-92 cluster expression in retinoblastoma. In addition, we showed that the miR 17-92 cluster plays a role in RB cell proliferation and invasion. |
| PubMed ID | 22969266 |
| Year | 2012 |
| Title | Oncogenic microRNA 17-92 cluster is regulated by epithelial cell adhesion molecule and could be a potential therapeutic target in retinoblastoma. |
| Drug-related ncRNA | NO |
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